Coris > Products > Proguanil-Strip > FAQ
No, only on urine specimen.
Yes. No interference of Atovaquone on the detection of Proguanil with "Proguanil-Strip" kit has been documented.
The line below red arrows indicates the limit that could not be passed beyond during incubation.
Depending on the assay tube used routinely in laboratories, it could happen that the limit line indicated on the sticker could be overcome. It can give rise to any problems on the result itself due to excessive dilution of adsorbed reagents in urine. One of them is adsorbed at 1.5 cm from the bottom of the stick. Incubation limit should not exceed 1,2cm, i.e. the red line indicated on the figure.
Control line is aimed to ensure that chromatography has been performed up to the top of the strip. It is not related with the result of the diagnostic itself.
Sometimes, the control line might be "slightly weak "without any precise reason. It could be only an effect of the sample migration and / or responsiveness at the control line. To sum up, the control line is aimed to validate the test using various specimen exists.
Indeed the product is stable during at least 20 weeks after first opening. 20 weeks is quite high: that means less than 3 tests per week. Stability is dependant of the storage conditions. Immunochromatographic test uses nitrocellulose support which is sensitive to humidity. That's why we put desiccant in the tube and in the cap.
In each case, there is an internal control (upper line). If this internal control appears during the run that means that the test is running well. We have to give a shelf life, but the test can be used after 20 weeks. The result will be valid if the control line appears.
No. Maybe the sticker (with arrows) covering the bottom of the nitrocellulose is peeled off. In this case, the test is invalidated. Please perform the test with another strip.
If the sample does not migrate due to the presence of particles, centrifuge the diluted sample. Collect the culture supernatant and perform the test again.
This is to avoid as far as possible.Test has been validated for 10-minutes of run.
No. Although 400µl is the optimal volume, test can be run in a urine volume in the range 200-500µl. Take care the level of the sample is below the red line under red arrows.
The kit specifically detects only the drug and NOT derived metabolites (detection of proguanil or chlorproguanil only).