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Projet scientifique RADAR

Le projet RADAR (COOTECH) à pour objectif de développer de nouveaux tests d’identification de résistances aux antibiotiques.

Ce projet réalisé par Coris BioConcept en partenariat avec la société Synabs passe par la création de réactifs nécessaires au développement de nouveaux tests ainsi qu’à l’amélioration de tests existants afin d’étendre leur champ d’utilisation et permettra à Coris BioConcept d’étendre la gamme R.E.S.I.S.T. dédiée à ces identifications.

Cette gamme de tests d’identification de résistances aux antibiotiques permettra aux laboratoires de diagnostic d’améliorer leurs réponses aux besoins des cliniciens pour mieux prendre en charge la prévention des infections et une utilisation raisonnée des antibiotiques.

Ce projet d’un budget de 1,66 millions d’euros est financé à hauteur de 570.600 euros par les sociétés partenaires et bénéficie de 1,09 millions d’euros de subsides publics (40% FEDER, 60% Région Wallonne).


Le Fonds européen de développement régional et la Wallonie
investissent dans votre avenir.

OXA-23 K-SeT: the new solution to detect OXA-23 carbapenemase


The global spread of carbapenem-resistant Acinetobacter spp., and particularly A. baumanii, in healthcare settings causes a major threat to patient survival. Worldwide, drug-resistant Acinetobacter spp. are responsible for serious nosocomial outbreaks, mostly in intensive care units. Even though different resistance mechanisms have been described, production of Amber Class D oxacillinases OXA-23-like hydrolysis enzymes is the most frequent acquired mechanism.

Fast and accurate detection of OXA-23-producing strains remains challenging at the laboratory level. Specific identification of oxacillinase-expressing Acinetobacter requires genotypic molecular assays that remain expensive and not commercially available. Immunochromatography lateral flow tests are however cost-effective and convenient to detect drug hydrolyzing enzymes.

Today, a large panel of lateral flow tests to detect carbapenemase-expressing Enterobacteriacea, named “RESIST”, is commercialized by the Belgian company Coris BioConcept. In order to fulfill the unmet need for fast and reliable detection of drug-resistant Acinetobacter, Coris BioConcept developed a new lateral flow assay, “OXA-23 K-SeT”, for the specific identification of OXA-23-mediated carbapenem-resistant in Acinetobacter spp. from a single colony.

With results available in less than 15 minutes, this easy-to-use and instrument-free rapid test represents the first phenotypic, specific and non-molecular confirmatory assay for OXA-23 detection. It will expand the RESIST range of products already adopted nowadays by routine and reference laboratories worldwide, offering an additional tool to ensure the successful treatment of patients and prevent the spread of carbapenemase-producing bacteria in healthcare settings.


OXA-23 K-SeT

TRAPIST, a new diagnostic system


Coris BioConcept has always been committed to developing new technologies and products so its customers can perform more rapidly and accurately the detection and identification of infectious agents.

For more than 6 years, Coris has set up throughout two european projects a new R&D diagnostic platform called TRAPIST : The Rapid Advanced PCR & Immunoassay SysTem.

TRAPIST V6 is a fully automated instrument that performs multiplex diagnostic testings.
It is intended to be used in clinical laboratories for fast and easy multiplex diagnostics with disposable microfluidic chips.
Results are available within an hour. The platform enables a wide range of molecular assays as well as immunoassays.

 Img_Blog_Trapist_Machine_cercle          Img_Blog_Trapist_Puce_cercle

Coris BioConcept’s lab-on-a-chip is a disposable device that combines multiplex PCR amplification and detection by hybridization on a membrane in a microfluidic environment.
Used in conjunction with the Trapist V6 automated system, the disposable microfluidic chip supports all the steps of a rapid, specific and sensitive multiplex diagnostic from a single DNA sample preparation.
DNA sample and reagents are introduced into the chip by a simple and convenient procedure before being automatically processed by the Trapist V6 system.
The entire chip is airtight, preventing carry-over contamination with amplified DNA.

Want to discover how it works ?

Contact us for more information


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