Is the buffer the same for all Coris BioConcept kits? If I need some more for my tests, may I use the one from another kit?

According to the "Instructions For Use" it is not allowed to exchange buffer between kits. If you face some volume problems, please contact your distributor.  He will provide you with some more vials. Nevertheless, within one product of different lot numbers, the buffer is the same (for instance, exchanging Rota-Strip buffers between lot will not give rise to any problems on the strips).

At present, 4 different kinds of buffers are used in Coris’products, i.e., Giardia Buffer (for Giardia-Strip), Extraction Buffer (for RSV-Strip), HC buffer (for GastroVir-Strip) and Dilution Buffer for all the other products.

Particularly for the GastroVir Kit we received some comments claiming that the Control Line was too faint. The buffer has been improved to allow a better migration of the latex microspheres leading to a better and a more homogeneous signal.  Of course this improvement does not affect the characteristics of the kit (i.e. specificity and sensitivity).

Why the kit doesn't contain loop and tube?

The kit doesn't contain the loop and the plastic tube because that material is very common in all labs. In general the labs obtain good price on the plastic disposable.
We want to offer the most competitive price which means that if we had to furnish this material, we would have to take a little margin on it to cover generated administrative costs and price of shipment would be higher.
On the economical point of view it is more interesting for the customer to buy loops and tubes himself.
With the dropper bottle, he doesn't have to use any micropipettes. He just needs one inoculating loops and one 3mL or 5 mL test tube.

How to use correctly Coris BioConcept's kits?

- Always store the strips' tube at the indicated storage temperature (between 4 and 30°C works for all kits)
- Always use gloves to touch the strips
- Always use the provided (Extraction or Dilution) Buffer even if the sample is already diluted (in a transport medium for instance)
- Always be sure that the solution is homogenous before testing
- Always be sure that the solution does not touch directly the gold conjugate (red zone on the strip)
- Always read the results when the stick is wet (between 10 and 15 minutes depending on the test)
- After opening of the tube containing the strips, quality is guaranteed during 15 weeks
- Always close the tube after each use to avoid that strips become wet. Take care to leave the desiccant inside the tube. - If storing the strips' tube at 4°C, always be sure to warm the tube at room temperature before opening.

Which is the difference between "Adeno-Strip" and "40/41 Adeno-Strip"? How do you suggest the use of each one?

There are several subgroups for Adenoviruses ranging from A to F. The F group only contains the adenoviruses types 40 and 41 responsible for diarrhoea.
So for a specific identification of enteric problems, it would be better to identify those 40/41 viruses.
The use of the Adeno-Strip or 40/41 Adeno-Strip depends on the routine practices relative to the physician. Some countries prefer to test all groups (using Adeno-Strip) while others are more oriented to testing the F group (using 40/41 Adeno-Strip).
The best way is to check the samples with Combi-Strip which can detect both Rota & Adenovirus group.
If sample is ADENO positive, we suggest to confirm the result with 40/41 Adeno-Strip.

Does the normal Adeno-Strip test detect all the different types, also 40/41?

Yes, the Adeno-Strip test detect all the different types including 40 and 41. The Adeno-Strip test uses monoclonals directed against the Hexon antigens present on all Adenovirus groups, including the F goup (40/41).

Does the faeces test also detect the types of Adenovirus that can be detect with the Adeno Respi-Strip?

The Adeno Respi-Strip test has been optimised in such a way that it can detect Adenovirus in respiratory samples in terms of quantity of virus and in terms of sample type. If you use the faecal test, you will face detectability problems.