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Launch of our new product : Clostridium difficile

Clostridium difficile is one of the most prevalent nosocomial pathogen mainly affecting patients after antibiotic treatment. Toxinogenic strains of C. difficile cause infections from mild diarrhoea to pseudomembranous colitis, potentially leading to death. The tissue-damaging enterotoxin (Toxin A) and the cytotoxin (Toxin B) produced by toxinogenic strains of C.difficile are responsible for the disease.

Due to the lack of sensitivity of toxins A&B rapid diagnostic tests, recommended algorithms for testing for toxinogenic C. difficile infection require detection of the C. difficile GDH as antigenic marker in stool as a first step. This test should have the highest possible sensitivity to ensure that no infected patients are missed.

Coris BioConcept Clostridium K-SeT allows the specific detection of C.difficile‘s GDH in stool specimen. There is a 100% concordance for detection of GDH between the Clostridium K-SeT test and an ELISA assay.  Moreover, another study shows a 100% NPV regarding culture.  This evaluation has been conducted in a reference lab in Brussels and compared to a test regarded as the reference test in the EC and the US.

This study has shown that the Coris test performs better than the reference one. Results have been submitted at the ICAAC meeting in San Francisco this year.

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